O3 Impact of hyperglycaemia and the therapeutic action of metformin on the length of the telomers

O3 Impact of hyperglycaemia and the therapeutic action of metformin on the length of the telomers

Blog Article

Introduction: Hyperglycemia is one of the most important factors that determine the production of oxidative stress and inflammation, processes that can accelerate telomere shortening.Objectives: The objectives were to analyse the absolute telomere length (aTL) in individuals with altered fasting glucose levels (AFG) compared to individuals with normal glucose levels (NFG).To study from a prospective controlled study, the variation in aTL in patients with decompensated type 2 diabetes (T2D) before and Stacks and Exhaust Parts after treatment.Materials and Methods: A population of 246 individuals of both genders was studied, which were divided into a group of individuals with blood glucose levels 50Y).A subgroup of 30 patients with newly diagnosed T2D was studied, at the beginning (T0), and at 6 months (T6) of a pharmacological treatment and hygienic-dietary measures with the objective of achieving DIESEL PROTEIN HOT CHOCOLATE metabolic compensation.

In both studies, the biochemical-clinical variables of all individuals and the aTL were determined by quantitative real-time PCR.Statistical analyses were performed using Graph Pad Prism and SPSS software.